Considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. Focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control.

Biology 2e is designed to cover the scope and sequence requirements of a typical two-semester biology course for science majors. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology includes rich features that engage students in scientific inquiry, highlight careers in the biological sciences, and offer everyday applications. The book also includes various types of practice and homework questions that help students understand—and apply—key concepts. The 2nd edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Art and illustrations have been substantially improved, and the textbook features additional assessments and related resources.

By the end of this section, you will be able to do the following:

Classify the different types of joints on the basis of structure
Explain the role of joints in skeletal movement

By the end of this section, you will be able to do the following:

Describe the symptoms, potential causes, and treatment of several examples of nervous system disorders

Depression (major depressive disorder or clinical depression) is a common but serious mood disorder. It causes severe symptoms that affect how you feel, think, and handle daily activities, such as sleeping, eating, or working.

" This course gives a historical perspective on financial panics. Topics include the growth of the industrial world, the Great Depression and surrounding events, and more recent topics such as the first oil crisis, Japanese stagnation, and conditions following the financial crisis of 2008."

How do we communicate with the outside world? How are our senses of vision, smell, taste and pain controlled at the cellular and molecular levels? What causes medical conditions like allergies, hypertension, depression, obesity and various central nervous system disorders? G-protein coupled receptors (GPCRs) provide a major part of the answer to all of these questions. GPCRs constitute the largest family of cell-surface receptors and in humans are encoded by more than 1,000 genes. GPCRs convert extracellular messages into intracellular responses and are involved in essentially all physiological processes. GPCR dysfunction results in numerous human disorders, and over 50% of all prescription drugs on the market today directly or indirectly target GPCRs.In this course, we will discuss GPCR signal transduction pathways, GPCR oligomerization and the diseases caused by GPCR dysfunction. We will study the structure and function of rhodopsin, a dim-light photoreceptor and a well-studied GPCR that converts light into electric impulses sent to the brain and leads to vision. We will also discuss how mutations in rhodopsin cause retinal degeneration and congenital night blindness. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

This course will introduce the student to the history of Europe from 1800 to present day. The student will learn about the major political, economic, and social changes that took place in Europe during this period including Industrial Revolution, the First and Second World Wars, imperialism, and the Cold War. By the end of this course, the student will understand how nationalism, industrialization, and imperialism fueled the rise of European nation-states in the nineteenth century, as well as how world war and oppressive regimes devastated Europe during the 1900s. Upon successful completion of this course, students will be able to: Think critically and analytically about European history in the nineteenth and twentieth centuries; Identify and analyze the varying causes and effects of the Industrial Revolution in Europe; Identify, describe, and analyze the development of a coherent set of ideologies in post-Napoleonic Europe: liberalism, socialism, Marxism, nationalism, and Romanticism; Identify and describe the causes and effects of the era of reform and revolution in Europe in the 1820s and 1830s, as well as analyze the Revolutions of 1848; Describe and analyze the effects of urbanizationĺÎĺĚ_ĺÜexpanding cities, rising public health risks, redefined social classes, the evolving nature of the family, and new developments in science and thought; Identify the age of nationalism in Europe between 1850 and 1914. Students will analyze FranceĺÎĺĺÎĺs Second Empire, ItalyĺÎĺĺÎĺs unification, GermanyĺÎĺĺÎĺs unification, and the modernization of Russia. Students will also be able to define the emergence of the modern nation-state during this period; Identify the causes and characteristics of EuropeĺÎĺĺÎĺs ĺÎĺĺĺŤNew ImperialismĄ_ĺĺö of the late nineteenth century. Students will also be able to describe and analyze responses to this imperialism in Africa, India, the Middle East, and the Far East; Assess how and why World War I erupted in 1914. Students will also be able to identify and describe the characteristics and impact of the Great War; Identify and describe the Russian Revolution of 1917, including the fall of the Romanov dynasty and the Bolshevik Revolution; Identify and describe the cultural and social problems that characterized post-WWI Europe. Students will be able to analyze Modernism, ethnic and economic problems in central and eastern Europe, and the Great Depression; Identify and describe the rise of authoritarian regimes in Europe during the 1920s and 1930s. Students will be able to analyze Stalinism, Fascism, and Nazism; Identify and describe the causes and conflicts of World War II. Students will also be able to analyze, identify, and describe the Holocaust; Analyze and explain the Cold War. Students will also be able to analyze, identify, and describe the collapse of Communism and the Soviet Union, as well as the end of the Cold War; Identify and describe the post-WWII social transformations in Europe, including the rise of feminism, the rise of counterculture, and new developments in both science and technology; Analyze and interpret primary source documents from the nineteenth and twentieth centuries, using historical research methods. (History 202)

Principles of Macroeconomics 2e covers the scope and sequence of most introductory economics courses. The text includes many current examples, which are handled in a politically equitable way. The outcome is a balanced approach to the theory and application of economics concepts. The second edition has been thoroughly revised to increase clarity, update data and current event impacts, and incorporate the feedback from many reviewers and adopters. Changes made in Principles of Macroeconomics 2e are described in the preface and the transition guide to help instructors transition to the second edition. The first edition of Principles of Macroeconomics by OpenStax is available in web view here.

By the end of this section, you will be able to:

Explain recessions, depressions, peaks, and troughs
Evaluate the importance of tracking real GDP over time

By the end of this section, you will be able to:

Explain historical patterns of unemployment in the U.S.
Identify trends of unemployment based on demographics
Evaluate global unemployment rates

Psychology is designed to meet scope and sequence requirements for the single-semester introduction to psychology course. The book offers a comprehensive treatment of core concepts, grounded in both classic studies and current and emerging research. The text also includes coverage of the DSM-5 in examinations of psychological disorders. Psychology incorporates discussions that reflect the diversity within the discipline, as well as the diversity of cultures and communities across the globe.Senior Contributing AuthorsRose M. Spielman, Formerly of Quinnipiac UniversityContributing AuthorsKathryn Dumper, Bainbridge State CollegeWilliam Jenkins, Mercer UniversityArlene Lacombe, Saint Joseph's UniversityMarilyn Lovett, Livingstone CollegeMarion Perlmutter, University of Michigan