This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

1. Introduction to Pharmacology
2. Introduction to Drug-Receptor Interactions and Pharmacodynamics
3. Factors Contributing to Drug Effect
4. Pharmacological Descriptors of Drug-Receptor Interactions
5. Drug Action vs. Drug Effect
6. Characteristics of Drug-Receptor Interactions:
7. Response to Excessive and Reduced Stimulation of Receptors:
8. Two Main Classes of Receptor Ligands in Pharmacology: Agonists & Antagonists
9. Receptor Allosteric Modulators
10. Competitive Antagonist vs. Negative Allosteric Modulator
11. Types of Drug-Drug Interactions
12. Introduction to Signal Transduction
13. Enzyme-Linked Receptors
14. G-Protein-Coupled Receptors
15. Nuclear Receptors
16. Receptor Regulation
17. Ion Channels
18. Agents and Actions of the Autonomic Nervous System
19. Agents and Actions of the Autonomic Nervous System: Autonomic Pharmacology Overview
20. Actions of the Autonomic Nervous System: Adrenergic Pharmacology
21. Agents and Actions of the Autonomic Nervous System: Parasympathetic Nervous System
22. Agents and Actions of the Autonomic Nervous System: Sympathetic Nervous System

Introducing public health ethics poses two special challenges. First, it is a relatively new field that combines public health and practical ethics. Its unfamiliarity requires considerable explanation, yet its scope and emergent qualities make delineation difficult. Moreover, while the early development of public health ethics occurred in a western context, its reach, like public health itself, has become global. A second challenge, then, is to articulate an approach specific enough to provide clear guidance yet sufficiently flexible and encompassing to adapt to global contexts. Broadly speaking, public health ethics helps guide practical decisions affecting population or community health based on scientific evidence and in accordance with accepted values and standards of right and wrong. In these ways, public health ethics builds on its parent disciplines of public health and ethics. This dual inheritance plays out in the definition the U.S. Centers for Disease Control and Prevention (CDC) offers of public health ethics: “A systematic process to clarify, prioritize, and justify possible courses of public health action based on ethical principles, values and beliefs of stakeholders, and scientific and other information” (CDC 2011). Public health ethics shares with other fields of practical and professional ethics both the general theories of ethics and a common store of ethical principles, values, and beliefs. It differs from these other fields largely in the nature of challenges that public health officials typically encounter and in the ethical frameworks it employs to address these challenges. Frameworks provide methodical approaches or procedures that tailor general ethical theories, principles, values, and beliefs to the specific ethical challenges that arise in a particular field. Although no framework is definitive, many are useful, and some are especially effective in particular contexts. This chapter will conclude by setting forth a straightforward, stepwise ethics framework that provides a tool for analyzing the cases in this volume and, more importantly, one that public health practitioners have found useful in a range of contexts. For a public health practitioner, knowing how to employ an ethics framework to address a range of ethical challenges in public health—a know-how that depends on practice—is the ultimate take-home message.

Reviews available here: https://open.umn.edu/opentextbooks/textbooks/public-health-ethics-global-cases-practice-and-context

Introducing public health ethics poses two special challenges. First, it is a relatively new field that combines public health and practical ethics. Its unfamiliarity requires considerable explanation, yet its scope and emergent qualities make delineation difficult. Moreover, while the early development of public health ethics occurred in a western context, its reach, like public health itself, has become global. A second challenge, then, is to articulate an approach specific enough to provide clear guidance yet sufficiently flexible and encompassing to adapt to global contexts. Broadly speaking, public health ethics helps guide practical decisions affecting population or community health based on scientific evidence and in accordance with accepted values and standards of right and wrong. In these ways, public health ethics builds on its parent disciplines of public health and ethics. This dual inheritance plays out in the definition the U.S. Centers for Disease Control and Prevention (CDC) offers of public health ethics: “A systematic process to clarify, prioritize, and justify possible courses of public health action based on ethical principles, values and beliefs of stakeholders, and scientific and other information” (CDC 2011). Public health ethics shares with other fields of practical and professional ethics both the general theories of ethics and a common store of ethical principles, values, and beliefs. It differs from these other fields largely in the nature of challenges that public health officials typically encounter and in the ethical frameworks it employs to address these challenges. Frameworks provide methodical approaches or procedures that tailor general ethical theories, principles, values, and beliefs to the specific ethical challenges that arise in a particular field. Although no framework is definitive, many are useful, and some are especially effective in particular contexts. This chapter will conclude by setting forth a straightforward, stepwise ethics framework that provides a tool for analyzing the cases in this volume and, more importantly, one that public health practitioners have found useful in a range of contexts. For a public health practitioner, knowing how to employ an ethics framework to address a range of ethical challenges in public health—a know-how that depends on practice—is the ultimate take-home message.

This casebook, now in its second edition, is a collaboration of over 90 individuals with expertise and training in public health pharmacy. A total of 54 chapters are presented, covering a broad array of topics relevant to pharmacy applications of public health. These topics include, but are not limited to, cross-cultural care, health literacy and disparities, infectious disease, health promotion and disease prevention, medication safety, structural racism, advocacy/policy analysis, chronic disease, women’s health, rural health, travel medicine and more. The book is designed to allow educators/students to choose chapters of interest as they feel suited, as each chapter is independent from the others. Each chapter contains learning objectives and an introduction to the topic, followed by a case and questions. The chapter closes with commentary from the authors and patient-oriented considerations for the topic at hand.

Table of Contents
1. An ounce of prevention: pharmacy applications of the USPSTF guidelines
2. Communicating health information: hidden barriers and practical approaches
3. Medication safety: to ‘error’ is human
4. Drawing the line: preventing sexually transmitted infections
5. Interprofessional collaboration: transforming public health through team work
6. HIV and hepatitis C co-infection: a double-edged sword
7. Ethical decision-making in global health: when cultures clash
8. Safe opioid use in the community setting: reverse the curse?
9. The ‘state’ of things: epidemiologic comparisons across populations
10. Saying what you mean doesn’t always mean what you say: cross-cultural communication
11. The cough heard ‘round the world: working with tuberculosis
12. More than just diet and exercise: social determinants of health and well-being
13. Deciphering immunization codes: making evidence-based recommendations
14. Getting to the point: importance of immunizations for public health
15. Smoke in mirrors: the continuing problem of tobacco use
16. Plant now, harvest later: services for rural underserved patients
17. Telepharmacy: building a connection to close the healthcare gap
18. Hormonal contraception: from emergency coverage to long-term therapy
19. From belly to baby: preparing for a healthy pregnancy
20. When disaster strikes: managing chaos and instilling lessons for future events
21. Anticipating anthrax and other bioterrorism threats
22. In the stroke of time: pharmacist roles in the management of cerebrovascular accident
23. Alcohol use disorder: beyond prohibition
24. Immunizing during a pandemic: considerations for COVID-19 vaccinations
25. Sweetening the deal: improving health outcomes for patients with diabetes mellitus
26. The hidden burden of hemodialysis: personal and economic impacts
27. Only a mirage: searching for healthy options in a food desert
28. Sex education: counseling patients from various cultural backgrounds
29. Harm reduction for people who use drugs: A life-saving opportunity
30. Digging deeper: improving health communication with patients
31. Equity for all: providing accessible healthcare for patients living with disabilities
32. Laying the foundation for public health priorities: Healthy People 2030
33. Staying on track: reducing missed immunization opportunities in the pediatric population
34. When love hurts: caring for patients experiencing interpersonal violence
35. Pharmacists and Medicare Part D: helping patients navigate their prescription benefits
36. Expanding the pharmacists’ role: assessing mental health and suicide
37. Bridging the gap between oncology and primary care: a multidisciplinary approach
38. A stigma that undermines care: opioid use disorder and treatment considerations
39. Deprescribing in palliative care: applying knowledge translation strategies
40. Let your pharmacist be your guide: navigating barriers to pharmaceutical access
41. Open-door policy: a window into creation, implementation, and assessment
42. PrEPare yourself: let’s talk about sex
43. Unexpected souvenirs: parasitic and vector-borne infections during and after travel
44. You say medication, I say meditation: effectively caring for diverse populations
45. The Sustainable Development Goals and pharmacy practice: a blueprint for health
46. Experiences of a Caribbean immigrant: going beyond clinical care
47. Medicine for the soul: spirituality in pharmacy
48. Uncrossed wires: working with non-English speaking patient populations
49. Unintended consequences of e-cigarette use: a public health epidemic
50. A toxic situation: the roles of pharmacists and poison control centers
51. Prescription for change: advocacy and legislation in pharmacy
52. Travel medicine: what you need to know before you go
53. A pharmacist’s obligation: advocating for change
54. The great undoing: a multigenerational journey from racism to social determinants of health

This casebook, now in its second edition, is a collaboration of over 90 individuals with expertise and training in public health pharmacy. A total of 54 chapters are presented, covering a broad array of topics relevant to pharmacy applications of public health. These topics include, but are not limited to, cross-cultural care, health literacy and disparities, infectious disease, health promotion and disease prevention, medication safety, structural racism, advocacy/policy analysis, chronic disease, women’s health, rural health, travel medicine and more. The book is designed to allow educators/students to choose chapters of interest as they feel suited, as each chapter is independent from the others. Each chapter contains learning objectives and an introduction to the topic, followed by a case and questions. The chapter closes with commentary from the authors and patient-oriented considerations for the topic at hand.

A framework of public hygiene and epidemiology is given. Human pathology related to water and sanitation is dealt with, as well as the relation between health and society and environment.

Pulmonary Pathophysiology for Pre-Clinical Students is an undergraduate medical-level resource for foundational knowledge of pulmonary pathophysiology. This text is designed for a course pre-clinical undergraduate medical curriculum and it is aligned to USMLE(r) (United States Medical Licensing Examination) content guidelines. The text is meant to provide the essential information from these content areas in a concise format that would allow learner preparation to engage in an active classroom. Clinical correlates and additional application of content is intended to be provided in the classroom experience. The text assumes that the students will have an understanding of basic cardiovascular physiology that will be helpful to understand the content presented here. This resource should be assistive to the learner later in medical school and for exam preparation given the material is presented in a succinct manner, with a focus on high-yield concepts.

This textbook was created for Austin Community College's Biotechnology Program online course: Quality Assurance for the Biosciences, BITC1340. The 10-chapter activity eBook covers quality assurance topics ranging from the history of quality and regulations in the US, an overview of the FDA and its structure and function, and the approval process for a variety of biotechnology products such as food, drugs, and medical devices. Throughout the eBook are exploratory activities, videos, and case studies.

What Is Nutrition Reality? Is it in the advertising claims that a food is natural or supplies instant energy? Is it in the myriad of dietary supplements? Is it in the diet plans for instant weight loss and glowing health? The only way to find out is to learn the basic principles of nutrition science, so you can be your own nutrition expert. Here is the true introduction to nutrition that you will read with pleasure and real understanding. It will free you from dependence on popular sources of information - often misinformation - so you can distinguish illusion from the realities of nutrition.

When two different strains of influenza infect a single cell, their genetic material can mix freely, resulting in a new third strain of influenza.

The interprofessional health care specialty of palliative care employs holistic evaluation and person-centered communication in the care of people with life-threatening illness. Palliative care clinicians are consulted for one or more of the following reasons:
- Symptom assessment and management
- Assistance with making difficult decisions about continued use or withdrawal of life-sustaining interventions
- Communication for planning the most appropriate care setting to meet person/family goals for end-of-life care
- Assessment of suitability and eligibility for hospice care

This resource is a compilation of previously published documents and tools useful to palliative care clinicians in preparing for and conduction these consultations. In addition, it can be a reference for students and clinical trainees doing course work, analyzing case studies, or simulating clinical communication scenarios. The materials are indexed for easy retrieval, referenced to acknowledge sources and allow further exploration, and organized into the following categories:
- Palliative Care Definitions/Domains/Dimensions
- Communication
- Symptom Assessment
- Functional Status Evaluation
- Prognostication
- End-of-Life Assessment and Management
- Symptom Management
- Hospice Eligibility Criteria
- Withholding and Withdrawing Life-Sustaining Interventions
- Pediatric End-of-Life Issues

This open access textbook is intended to guide best practices in the journey of scholarly writing in the context of the nursing profession. This resource is designed for students in undergraduate nursing programs and may also be useful for students in other health-related post-secondary programs, graduate students, and healthcare providers. The project is supported and funded by the Ryerson University Library OER Grant.

Table of Contents:

Chapter 1: Introduction
Chapter 2: Reading and Comprehension
Chapter 3: Information Literacy
Chapter 4: Types of Writing
Chapter 5: The Fundamentals of Writing
Chapter 6: The Writing Process and Pre-Writing
Chapter 7: Drafting and Writing a Paper
Chapter 8: Revising and Editing a Paper
Chapter 9: Academic Integrity and Style Rules (APA 6th edition)
Chapter 10: Academic Integrity and Style Rules (APA 7th edition)

For the course NUFS 016: Science, Physiology, and Nutrition

A wonderful blend of physiology, nutrition, biochemistry, genetics, biology, evolution, chemistry--what we all need to know as informed citizens. A basic knowledge of the life sciences and how our bodies work--to promote our own good health, especially as we're bombarded with misleading advertisements, soundbites, and the like. DNA fingerprinting, calorie requirements, dietary advice, genetic engineering (including gene editing with CRISPR cas9)--all in an easy-to understand book.

This course provides an introduction to life sciences, from chemistry to cellular and physiologic functions, with nutrition as an underlying theme. Interactions with environment, including effect of culture, genetics, and nutrition on susceptibility to disease. Applications of biotechnology in the life sciences.

The Science of Sleep teaches us the vital importance of sleep and how it determines our mental and physical health. It explores the neuroscience of sleep and cultural, social, and political aspects of how people view sleep and are affected by sleep.

Subject presents a range of advanced topics in integrated logistics and supply chain management. Conducted in a lecture-discussion format, with participation of corporate executives as guest lecturers. Students prepare industry assessment analyses and make formal classroom presentations. Specific topics alternate from year to year, but basic content includes procurement strategies and strategic sourcing, dynamic pricing and revenue management tactics, mitigation of supply chain risk through supply contracts, strategic outsourcing of supply chain chain functions and operations, management and operation of third party logistics providers, and management of supply chain security.

SEHRA (Sunshine EHR Academic), is an educational simulation of an electronic health records system using Access 2019 as the development platform. Piloted in December of 2019, SEHRA was successfully implemented in January of 2020, and became an essential part of SUNY Broome’s ability to take health science classes and clinicals online in March of 2020 in response to the COVID-19 pandemic. SEHRA continues to grow and is currently used in on-campus laboratories, remote courses, and for professional practice experience.

This Access database allows students in the various Business and Health departments to practice using an EHR during their labs, simulations, and assignments. As an MS Access file, not an online resource, users will need the appropriate software and operating system to run the simulation.

Provides graduate students and fellows with techniques that enhance both validity and responsible conduct in scientific practice. Topics include study design, laboratory practice, treatment of data, human and animal research, intellectual property, preparation of proposals, research papers, posters, and oral presentations. Also discussed are mentoring relationships and career options. Aspects of responsible research conduct are integrated as appropriate to the specific topic under discussion. Subject satisfies the training grant requirements of the NIH for education in the responsible conduct of research. This course is designed to provide graduate students and postdoctoral associates with techniques that enhance both validity and responsible conduct in scientific practice. Lectures present practical steps for developing skills in scientific research and are combined with discussion of cases. The course covers study design, preparation of proposals and manuscripts, peer review, authorship, use of humans and non-human animals in research, allegations of misconduct, and intellectual property. Also discussed are mentoring relationships and career options. Aspects of responsible research conduct are integrated into lectures and case discussion as appropriate to the specific topic. This course also satisfies the training grant requirements of the NIH for education in the responsible conduct of research.

Welcome to the online coursebook for our Theories and Biological Basis of Addiction course. The material is designed to be read interactively or after downloading; while the embedded interactive exercises require internet connectivity, each can also be downloaded for offline work. These exercises are presented to help you test and apply what you are reading, challenge yourself, prepare for quizzes, and have a little fun along the way. The list of key terms at the end explains text highlighted in bold italics throughout the book—in the interactive mode you can click on a highlighted word to jump to its explanation in the key terms section. Use the back arrow to return to where you were reading.

Transitions to Professional Nursing Practice provides a pivotal learning experience for students transitioning from an associate degree education to a baccalaureate degree. Content includes a broad overview of the nursing profession, the role of accrediting and professional organizations with a strong focus on the American Nurses Association’s foundational documents. The competencies of the Standards of Professional Practice and the Code of Ethics are weaved throughout the text.

Topics covered in this text include professional nursing practice, baccalaureate education, healthcare in the 21st century, autonomy and accountability, nursing philosophy, professional development, communication, interprofessional collaboration, critical thinking, introduction to evidence-based practice, and nursing leadership and theory.

Chapter 1
Professional Nursing Practice
Baccalaureate Education
Healthcare in the 21st Century
Accountability
Autonomy
References

Chapter 2
Nursing Philosophy
Professional Development
References

Chapter 3
Interprofessional Communication
Interprofessional Collaboration
Critical Thinking
Evidence-Based Practice
References

Chapter 4
Leadership in Nursing
References

Chapter 5
Nursing Theory
References

Chapter 6
Professional Organizations
References