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  • Immune System
B Cells
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So named as they were initially found in the Bursa of Fabricius, B cells produce antibodies and are associated with humoral immunity (T cells are part of the cell-mediated immune response), and are an integral part of the adaptive immune system. They represent 20-30% of circulating lymphocytes.

Subject:
Natural Science
Material Type:
Diagram/Illustration
Reading
Provider:
WikiVet
Provider Set:
Blood
Date Added:
12/27/2018
Biology 2e
Unrestricted Use
CC BY
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Biology 2e is designed to cover the scope and sequence requirements of a typical two-semester biology course for science majors. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology includes rich features that engage students in scientific inquiry, highlight careers in the biological sciences, and offer everyday applications. The book also includes various types of practice and homework questions that help students understand—and apply—key concepts. The 2nd edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Art and illustrations have been substantially improved, and the textbook features additional assessments and related resources.

Subject:
Biology
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
03/07/2018
Biology 2e, Animal Structure and Function, The Immune System, Innate Immune Response
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CC BY
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By the end of this section, you will be able to do the following:

Describe physical and chemical immune barriers
Explain immediate and induced innate immune responses
Discuss natural killer cells
Describe major histocompatibility class I molecules
Summarize how the proteins in a complement system function to destroy extracellular pathogens

Subject:
Applied Science
Material Type:
Module
Date Added:
09/20/2018
Biology 2e, Preface, Preface
Unrestricted Use
CC BY
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Applied Science
Material Type:
Module
Date Added:
09/20/2018
Biology: Types of Immune Responses: Innate and Adaptive.  Humoral vs. Cell-Mediated
Conditional Remix & Share Permitted
CC BY-NC-SA
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This 8-minute video lesson presents an overview of types of immune responses. It looks at the difference between innate and adaptive immunity and the differences between humoral adaptive immunity and cell-mediated adaptive immunity. [Biology playlist: Lesson 52 of 71].

Subject:
Biology
Material Type:
Lecture
Provider:
Khan Academy
Provider Set:
Khan Academy
Author:
Salman Khan
Date Added:
11/12/2019
Cells of the Immune System
Read the Fine Print
Educational Use
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This tutorial provides an overview of the immune system, concentrating on the roles played by B and T lymphocytes, and on the antigen-presentation system.

All animals possess a nonspecific defense system called the innate immune system, which includes macrophages in mammals. Vertebrates have an additional powerful immune response called adaptive immunity. This Click & Learn describes key elements of the adaptive immune system, including B cells and antibody molecules, helper T cells and cytotoxic T cells, and antigen presentation.

Subject:
Biology
Material Type:
Activity/Lab
Author:
Howard Hughes Medical Institute
Date Added:
09/10/2019
Cellular and Molecular Immunology, Fall 2005
Conditional Remix & Share Permitted
CC BY-NC-SA
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Covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation including molecular structure and assembly of MHC molecules, lymphocyte activation, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases. Consists of lectures and tutorials in which clinical cases are discussed with faculty tutors. Details of the case covering a number of immunological issues in the context of disease are posted on a student Web site.

Subject:
Biology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Pillai, Shiv
Date Added:
01/01/2005
Cloning an Army of T Cells for Immune Defense
Restricted Use
Copyright Restricted
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View the animation to see how one type of immune cell-the helper T cell-interprets a message presented at the surface of the cell membrane. The message is an antigen, a protein fragment taken from an invading microbe. A series of events unfolds that results in the production of many clones of the helper T cell. These identical T cells can serve as a brigade forming an essential communication network to activate B cells, which make antibodies that will specifically attack the activating antigen.

Subject:
Health, Medicine and Nursing
Chemistry
Material Type:
Lecture
Provider:
Howard Hughes Medical Institute
Date Added:
04/10/2012
Evolution of the Immune System, Spring 2005
Conditional Remix & Share Permitted
CC BY-NC-SA
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Seminar covering topics of current interest in biology. Includes reading and analysis of research papers and student presentations. Contact Biology Education Office for topics.

Subject:
Biology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Danilova, Nadia
Date Added:
01/01/2005
Human Physiology
Unrestricted Use
CC BY
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Physiology is the study of the processes of the body. This course is about the unconscious mechanics of living; the student will look at each organ system in detail and then discuss the ways in which the systems interact in order to maintain the body at an optimal state. Metabolism and homeostasis--or the maintenance of the body at a set, optimal level--will be the primary themes. Upon successful completion of this course, the student will be able to: describe the relationship between structure and function at the cellular level and relate dysfunctional states of health to problems at the cellular level when appropriate; given relevant physiological information, explain the physiological mechanisms involved; describe the concepts of homeostasis and feedback control in relationship to each organ system; use a vocabulary of physiological terms and demonstrate an ability to communicate efficiently in a medical environment; describe techniques currently in use that measure the function of organ systems. (Biology 304)

Subject:
Anatomy/Physiology
Material Type:
Full Course
Provider:
The Saylor Foundation
Date Added:
04/29/2019
Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance, Spring 2004
Conditional Remix & Share Permitted
CC BY-NC-SA
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This course is an advanced undergraduate seminar based upon discussions and critical analysis of primary literature in the field of immunology. Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease specific immune evasion and the mechanisms used by pathogens to prevail over their host's immune systems are discussed. What these host-pathogen interactions reveal about the normal function of the immune system and about basic cell biological processes, such as protein maturation and degradation, are also considered.

Subject:
Biology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Halme, Dina Gould
Date Added:
01/01/2004
Immunology
Unrestricted Use
CC BY
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This sequence explores the elements of innate and acquired immune defense mecahnisms, the cells involved, their development and maturation, and biomolecular cellular communication mechanisms required to successfully fight off infection.

Subject:
Biology
Immunology
Material Type:
Full Course
Author:
Wesley Dunnick
Date Added:
02/25/2019
Immunology
Unrestricted Use
CC BY
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Immunology is the study of our immune system, a highly sophisticated system that defends us against all disease-causing invaders by identifying and neutralizing such threats. As with any system in our body, when the immune system malfunctions, disease can result. In this course the student will take a look at what happens when an inappropriate immune response takes place. (Biology 407)

Subject:
Health, Medicine and Nursing
Material Type:
Full Course
Provider:
The Saylor Foundation
Date Added:
04/29/2019
Immunology Lecture Series
Restricted Use
Copyright Restricted
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This 4-lecture series covers the basics of the immune system, how T cells work, how MHC proteins affect our susceptibility to autoimmune diseases, and the relationship between the immune system and infectious diseases.

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
Howard Hughes Medical Institute
Author:
John W. Kappler, Ph.D.
Philippa Marrack, Ph.D.
Date Added:
04/24/2012