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Anatomy and Physiology I Lab Manual
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This lab manual was created for Anatomy and Physiology I at the University of Georgia under a Textbook Transformation Grant and revised through a Scaling Up OER Pilot Grant.

The manual contains labs on cells, histology, the integumentary system, the skeletal system, the nervous system, muscles, and the senses.

Subject:
Anatomy/Physiology
Material Type:
Activity/Lab
Reading
Syllabus
Author:
Daniel McNabney
DeLoris Hesse
Date Added:
01/23/2020
Biology 2e
Unrestricted Use
CC BY
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Biology 2e is designed to cover the scope and sequence requirements of a typical two-semester biology course for science majors. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology includes rich features that engage students in scientific inquiry, highlight careers in the biological sciences, and offer everyday applications. The book also includes various types of practice and homework questions that help students understand—and apply—key concepts. The 2nd edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Art and illustrations have been substantially improved, and the textbook features additional assessments and related resources.

Subject:
Biology
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
03/07/2018
Biology 2e, Preface, Preface
Unrestricted Use
CC BY
Rating

Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Applied Science
Material Type:
Module
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
09/20/2018
Cell Biology
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CC BY
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This course will present the student with a detailed overview of a cell's main components and functions. The course is roughly organized into four major areas: the cell membrane, cell nucleus, cell cycle, and cell interior. The student will approach most of these topics straightforwardly, from a molecular and structural point of view. Upon completion of this course, the student will be able to: explain what a eukaryotic cell is, identify the components of the cell, and describe how a cell functions; explain how cell membranes are formed; identify the general mechanisms of transport across cell membranes; list the different ways in which cells communicate with one another--specifically, via signaling pathways; define what the extracellular matrix is composed of in different cells and how the extracellular matrix is involved in forming structures in specific tissues; list the components of the cell's cytoskeleton and explain how the cytoskeleton is formed and how it directs cell movements; explain the fundamentals of gene expression and describe how gene expression is regulated at the protein level; define and explain the major cellular events involved in mitosis and cytokinesis; identify the major cellular events that occur during meiosis; describe the eukaryotic cell cycle and identify the events that need to occur during each phase of the cell cycle; identify all of the major organelles in eukaryotic cells and their respective major functions. (Biology 301)

Subject:
Biology
Material Type:
Full Course
Provider:
The Saylor Foundation
Date Added:
04/29/2019
Cell Biology, Spring 2007
Conditional Remix & Share Permitted
CC BY-NC-SA
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Biology of cells of higher organisms: structure, function, and biosynthesis of cellular membranes and organelles; cell growth and oncogenic transformation; transport, receptors and cell signaling; the cytoskeleton, the extracellular matrix, and cell movements; chromatin structure and RNA synthesis.

Subject:
Biology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Orr-Weaver, Terry
Date Added:
01/01/2007
Cell and Molecular Neurobiology, Spring 2008
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CC BY-NC-SA
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Subject covers all major areas of cellular and molecular neurobiology including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell type determination, axon guidance and targeting, neuronal cell biology, synapse formation and plasticity. Includes lectures and exams, and involves presentation and discussion of primary literature. Focus on major concepts and recent advances in experimental neuroscience.

Subject:
Biology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Constantine-Paton, Martha
Sheng, Morgan
Date Added:
01/01/2008
Cellular Metabolism and Cancer: Nature or Nurture? (Fall 2018)
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CC BY-NC-SA
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In this course we will explore how altered metabolism drives cancer progression. Students will learn (1) how to read, discuss, and critically evaluate scientific findings in the primary research literature, (2) how scientists experimentally approach fundamental issues in biology and medicine, (3) how recent findings have challenged the traditional “textbook” understanding of metabolism and given us new insight into cancer, and (4) how a local pharmaceutical company is developing therapeutics to target cancer metabolism in an effort to revolutionize cancer therapy.

Subject:
Health, Medicine and Nursing
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Allison Lau
Evan Lien
Date Added:
01/01/2018
Coagulation Tests
Only Sharing Permitted
CC BY-NC-ND
Rating

It is important that all aspects of haemostasis can be independently evaluated. This will help to identify the phase affected and to pinpoint what the abnormality is. There are tests available to assess primary haemostasis, secondary haemostasis and fibrinolysis.

Subject:
Natural Science
Material Type:
Diagram/Illustration
Reading
Provider:
WikiVet
Provider Set:
Blood
Date Added:
12/27/2018
Concepts of Biology Canvas Course Shell
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CC BY-NC
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This is a Canvas course shell that can be imported into your Canvas course and modified to fit your needs.

Subject:
Biology
Material Type:
Diagram/Illustration
Full Course
Homework/Assignment
Lecture
Lecture Notes
Module
Reading
Student Guide
Syllabus
Teaching/Learning Strategy
Unit of Study
Provider:
LOUIS: The Louisiana Library Network
Author:
Tracie Rizan Bates
Date Added:
03/11/2021
The DNA Damage Response as a Target for Anti-Cancer Therapy, Fall 2008
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Cellular responses to DNA damage constitute one of the most important fields in cancer biology. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understand of cell cycle regulation and DNA damage checkpoints that act as powerful emergency brakes to prevent cancer. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Subject:
Biology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Reinhardt, Hans Christian
Date Added:
01/01/2008
Digital Histology
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CC BY-NC-SA
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Digital Histology is organized as chapters that parallel those of most histology textbooks. Each of the over 1600 pages contains an original, high quality image accompanied by descriptive text and selectable labels. In addition, interactive quizzes with formative feedback accompany each chapter of Digital Histology. A review textbook with hyperlinks to images in the main package is also included. A brief introductory video is available here: Introduction to Digital Histology | https://www.youtube.com/watch?v=ODsxTdKD9og&feature=youtu.be

Subject:
Biology
Material Type:
Diagram/Illustration
Textbook
Author:
Alice S. Pakurar
John W. Bigbee
Date Added:
02/03/2020
Erythropoiesis
Only Sharing Permitted
CC BY-NC-ND
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Erythrocytes contain no nucleus and are thus only produced from stem cells. During the fetal stage production is in both the liver and spleen however production is transferred to the bone marrow (red marrow) in the final stages of gestation. Initially erythropoiesis occurs in all bones, however after puberty production is limited to membranous bones (ribs, vertebrae, pelvic bones etc.) as the long bones contain adipose tissue in place of red marrow.

Subject:
Natural Science
Material Type:
Diagram/Illustration
Reading
Provider:
WikiVet
Provider Set:
Blood
Date Added:
12/27/2018
The Fountain of Life: From Dolly to Customized Embryonic Stem Cells, Fall 2007
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" During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimentally proven. Only 10 years ago the sheep Dolly was the first mammal to be cloned from an adult organism, demonstrating that the differentiated state of a mammalian cell can be fully reversible to a pluripotent embryonic state. A key conclusion from these experiments was that the difference between pluripotent cells such as embryonic stem (ES) cells and unipotent differentiated cells is solely a consequence of reversible changes. These changes, which have proved to involve reversible alterations to both DNA and to proteins that bind DNA, are known as epigenetic, to distinguish them from genetic alterations to DNA sequence. In this course we will explore such epigenetic changes and study different approaches that can return a differentiated cell to an embryonic state in a process referred to as epigenetic reprogramming, which will ultimately allow generation of patient-specific stem cells and application to regenerative therapy. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching."

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Meissner, Alexander
Date Added:
01/01/2007
General Biology I
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CC BY-NC-SA
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An integrated course stressing the principles of biology. Life processes are examined primarily at the molecular and cellular levels. Intended for students majoring in biology or for non-majors who wish to take advanced biology courses.

Subject:
Biology
Genetics
Chemistry
Material Type:
Activity/Lab
Full Course
Lecture Notes
Syllabus
Provider:
UMass Boston
Provider Set:
UMass Boston OpenCourseWare
Author:
Ph.D.
Professor Brian White
Date Added:
04/25/2019
General Biology I: Survey of Cellular Biology
Unrestricted Use
CC BY
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BI101: Survey of Cellular Biology is intended for one term of the introductory biology course for non-science majors taught at many two- and four-year colleges. The concepts of cellular biology, as they apply to the study of life, are introduced, including parts of a cell, metabolism, and homeostasis.

This textbook incorporates the mandates found in Vision and Change and focuses on the non-content aspects of biology education that are just as important. Additionally, this book explicitly teaches the general education outcomes that we have identified as important for this class. This textbook pulls together biology content resources that are accessible for our community college non-major biology students, as well as resources to provide them with explicit instruction in the quantitative literacy, communication, and information literacy general education outcomes as they relate to the biology content they are learning.

Contact the author for inquiries about quiz

Table of Contents
I. 1. Reference Information
II. The Process of Science
III. Themes and Concepts of Biology
IV. Cell Structure and Function
V. Membranes and movement of molecules
VI. Enzyme-catalyzed reactions
VII. How cells obtain energy
VIII. Photosynthesis

Subject:
Biology
Material Type:
Textbook
Provider:
OpenOregon
Author:
Christine Anderson
Lisa Bartee
Date Added:
09/07/2016
Human Biology
Unrestricted Use
CC BY
Rating

This textbook has been created with several goals in mind: accessibility, customization, and student engagement—all while encouraging students toward high levels of academic scholarship. Students will find that this textbook offers a strong introduction to human biology in an accessible format.

Table of Contents
Chapter 1: Introduction to Human Biology and the Scientific Method
Chapter 2: Chemistry and Life
Chapter 3: Cells
Chapter 4: DNA and Gene Expression
Chapter 5: Digestive System
Chapter 6: Energy Considerations
Chapter 7: Blood
Chapter 8: Heart
Chapter 9: Blood Vessels
Chapter 10: Respiratory System
Chapter 11: Hormones
Chapter 12: Urinary System
Chapter 13: Mitosis and Meiosis
Chapter 14: Reproductive Systems
Chapter 15: Skeletal System
Chapter 16: Muscles and Movement
Chapter 17: Nervous System
Chapter 18: Special Senses
Chapter 19: Immune System

Subject:
Biology
Material Type:
Textbook
Author:
Willy Cushwa
Date Added:
09/06/2019
Immunology
Unrestricted Use
CC BY
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Immunology is the study of our immune system, a highly sophisticated system that defends us against all disease-causing invaders by identifying and neutralizing such threats. As with any system in our body, when the immune system malfunctions, disease can result. In this course the student will take a look at what happens when an inappropriate immune response takes place. (Biology 407)

Subject:
Health, Medicine and Nursing
Material Type:
Full Course
Provider:
The Saylor Foundation
Date Added:
04/29/2019
Introduction to Molecular and Cellular Biology
Unrestricted Use
CC BY
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Though biology as we know it today is a relatively new field, we have been studying living things since the beginning of recorded history. This introductory course in biology starts at the microscopic level, with molecules and cells, then moves into the specifics of cell structure and behavior. Upon successful completion of this course, students will be able to: Describe in general terms how life began on Earth; Identify early scientists that played important roles in furthering our understanding of cellular life; Describe the characteristics that define life; List the inorganic and organic molecules that are necessary for life; List the structure and function of organelles in animal and plant cells; List the similarities and differences between animal and plant cells; Describe the reactions in photosynthesis; Explain how the different photosynthetic reactions are found in different parts of the chloroplast; Describe the sequence of photosynthetic reactions; Explain the use of products and the synthesis of reactants in photosynthesis; Explain how protein is synthesized in eukaryotic cells; Describe the similarities and differences between photosynthesis and aerobic respiration; List the reactions in aerobic respiration; Explain the use of products and the synthesis of reactants in aerobic respiration; Describe the similarities and differences between anaerobic and aerobic respiration. (Biology 101; See also: Psychology 203)

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
The Saylor Foundation
Date Added:
04/29/2019
Introduction to Molecular and Cellular Biology - Laboratory
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CC BY
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This lab course supplements Introduction to Molecular and Cellular Biology. Although it does not replicate a true lab experience, it does enable further exploration of some key principles of molecular and cellular biology. In each unit, the student will work through tutorials related to important scientific concepts, and then will be asked to think creatively about how those concepts can be put to practical or experimental use. This lab course also contains activities devoted to learning important techniques in scientific study such as microscope use, DNA extraction, Polymerase Chain Reaction, and examination of DNA microarrays. Upon successful completion of this lab supplement, students will be able to: Identify the important components of scientific experiments and create their own experiments; Identify the molecular differences between proteins, fats, and carbohydrates, and explain the molecular behavior of water; Describe the process of photosynthesis; Describe the process of cellular respiration; Identify the differences between DNA and RNA; Describe the entire transcription/translation process, from gene to protein; Explain how recombinant genomes are formed; Use critical thinking to find ways that any of the above natural processes might be altered or manipulated; Explain how to use a compound light microscope for data collection; Explain how to conduct and use various experimental techniques, including DNA extraction, PCR, and DNA microarrays. (Biology 101 Laboratory)

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
The Saylor Foundation
Date Added:
04/29/2019
Introductory Medical Microbiology Ancillary Materials
Unrestricted Use
CC BY
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This set of lecture materials, laboratory notes, and activities are ancillary materials created for use with OpenStax Microbiology. The materials were created under a Round Nine Textbook Transformation Grant.

Topics covered include:

The Cell
Prokaryotes
Eukaryotes
Acellular Pathogens
Microbial Metabolism
Microbial Growth
Biochemistry of the Bacterial Genome
Microbial Genetics
Microbial Growth
Antimicrobial Drugs
Pathogenicity
Epidemiology
Immune System

Subject:
Biology
Material Type:
Full Course
Provider:
University System of Georgia
Provider Set:
Galileo Open Learning Materials
Author:
Andrew Dawson
Veronica Morin
Date Added:
06/20/2018
Microscopic Anatomy
Unrestricted Use
CC BY
Rating

In this course, the student will study microscopic anatomy. The course begins with an overview of basic cell structure follow by an explanation of how single cells come together to make up tissues. The student will then study each of the organ systems in the body, understanding how these tissues fit together structurally to form organs and organ systems that carry out specific functions. Upon successful completion of this course, the student will be able to: differentiate among the types of microscopy and describe the importance of microscopes in microscopic anatomy; correctly use the compound light microscope with a working knowledge of the function of each part; identify the organelles within a eukaryotic cell and list the basic function of each; compare and contrast meiosis and mitosis, identifying the steps of each in microscopic images; outline what makes each epithelial, connective, nervous, and muscle tissue unique, where each is found within the body, and how each interacts with other tissue types; point out circulatory system features, including intercalated disks and valves, as well as the differences among different vessel types; identify the cells found in blood and the role of each; define how the tissues and anatomical features that make up the gastrointestinal and respiratory systems come together structurally to support the function of these organ systems; identify the features of the epidermis and dermis of the skin, including the cells, layers, glands, and other features of each layer; explain how the structural arrangement of the lymphatic system and lymph node supports its physiological role of filtering; compare and contrast the structural arrangement of spongy and compact bone; map out the path of plasma filtrate as it moves through the neuron and into the ureter, bladder, and urethra, identifying what types of cells are located in each part; describe the basic structure of endocrine organs, including the reproductive organs; identify what features make special senses tissue unique. (Biology 406)

Subject:
Anatomy/Physiology
Biology
Material Type:
Full Course
Provider:
The Saylor Foundation
Date Added:
04/29/2019
Nanomechanics of Materials and Biomaterials, Spring 2007
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CC BY-NC-SA
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This course focuses on the latest scientific developments and discoveries in the field of nanomechanics, the study of forces and motion on extremely tiny (10-9 m) areas of synthetic and biological materials and structures. At this level, mechanical properties are intimately related to chemistry, physics, and quantum mechanics. Most lectures will consist of a theoretical component that will then be compared to recent experimental data (case studies) in the literature. The course begins with a series of introductory lectures that describes the normal and lateral forces acting at the atomic scale. The following discussions include experimental techniques in high resolution force spectroscopy, atomistic aspects of adhesion, nanoindentation, molecular details of fracture, chemical force microscopy, elasticity of single macromolecular chains, intermolecular interactions in polymers, dynamic force spectroscopy, biomolecular bond strength measurements, and molecular motors.

Subject:
Biology
Genetics
Chemistry
Physics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Ortiz, Christine
Date Added:
01/01/2007
OpenStax Biology
Unrestricted Use
CC BY
Rating

Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Natural Science
Biology
Material Type:
Full Course
Author:
Julie Adams
Summer Allen
Date Added:
10/03/2018
Principles of Radiation Interactions, Fall 2004
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CC BY-NC-SA
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Explores the interaction of radiation with matter at the microscopic level from both the theoretical and experimental viewpoints. Emphasis on radiation effects in biological systems. Topics include energy deposition by various types of radiation, including the creation and behavior of secondary radiations; the effects of radiation on cells and on DNA; and experimental techniques used to measure these radiation effects. Cavity theory, microdosimetry and methods used to simulate radiation track structure are reviewed. Examples of current literature used to relate theory, modeling, and experimental methods. Requires a term paper and presentation. The central theme of this course is the interaction of radiation with biological material. The course is intended to provide a broad understanding of how different types of radiation deposit energy, including the creation and behavior of secondary radiations; of how radiation affects cells and why the different types of radiation have very different biological effects. Topics will include: the effects of radiation on biological systems including DNA damage; in vitro cell survival models; and in vivo mammalian systems. The course covers radiation therapy, radiation syndromes in humans and carcinogenesis. Environmental radiation sources on earth and in space, and aspects of radiation protection are also discussed. Examples from the current literature will be used to supplement lecture material.

Subject:
Environmental Science
Education
Educational Technology
Physics
Material Type:
Activity/Lab
Assessment
Diagram/Illustration
Full Course
Homework/Assignment
Lecture Notes
Syllabus
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Coderre, Jeffrey A.
Date Added:
01/01/2004
Quantitative Physiology: Cells and Tissues, Fall 2004
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CC BY-NC-SA
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Principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Mass transport through membranes: diffusion, osmosis, chemically mediated, and active transport. Electric properties of cells: ion transport; equilibrium, resting, and action potentials. Kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the concepts. For juniors and seniors. Students engage in extensive written and oral communication exercises.

Subject:
Computer Science
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Freeman, Dennis
Date Added:
01/01/2004