A grasp of the logic and practice of science is essential to understand the rest of the world around us. To that end, the CMB4e iText (like earlier editions) remains focused on experimental support for what we know about cell and molecular biology, and on showing students the relationship of cell structure and function. Rather than trying to be a comprehensive reference book, CMB4e selectively details investigative questions, methods and experiments that lead to our understanding of cell biology. This focus is nowhere more obvious than in the chapter learning objectives and in external links to supplementary material. The Basic CMB3e version of the iText includes links to external web-sources as well as the author’s short, just-in-time YouTube VOPs (with edited, optional closed captions), all embedded in or near relevant text. Each video is identified with a descriptive title and video play and QR bar codes.

This exercise contains two interrelated modules that introduce students to modern biological techniques in the area of Bioinformatics, which is the application of computer technology to the management of biological information. The need for Bioinformatics has arisen from the recent explosion of publicly available genomic information, such as that resulting from the Human Genome Project.

Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology.

Table of Contents
Anatomy of a Cell
Basic Cell Chemistry
Bioenergetics
Membranes
Metabolism 1
Metabolism 2
DNA
Transcription
Gene Regulation
Translation
ER, Golgi, and Vesicles
Cytoskeleton
ECM and Adhesion
Cell Communication
Cell Cycle
Advanced Topics

This textbook, a remix of other open educational resources, is developed through a Round 15 Textbook Transformation Grant.

Table of Contents
Chapter 1 - Cytoskeleton
Chapter 2 - DNA Packaging and Chromosomes
Chapter 3 - Transcription and mRNA Modification
Chapter 4 - Translation
Chapter 5 - Transcriptional Regulation
Chapter 6 - Cell and Organelle Membrane Structure
Chapter 7 - Transport Across Cellular Membranes
Chapter 8 - The Electrochemical Gradient
Chapter 9 - Protein Trafficking
Chapter 10 - Vesicles in the Endomembrane System
Chapter 11 - Principles of Cell Signaling
Chapter 12 - GPCRs and RTKs
Chapter 13 - The Cell Cycle and Its Regulation
Chapter 14 - DNA Replication
Chapter 15 - Cell Death and Cancer
Chapter 16 - Stem Cells
Attributions

This course is the first in a three-course sequence that introduces biology in preparation for advanced study in areas of biological science such as medicine, dentistry, cell biology, microbiology, or veterinary medicine. Biol& 211 introduces students to cellular structure and function. Major topics studied include: energy capture and utilization, cellular reproduction, inheritance, genetic mutation, protein synthesis, gene expression, and biotechnology.