Chromosomal Basis of Inherited Disorders

Review Questions

Which of the following codes describes position 12 on the long arm of chromosome 13?

  1. 13p12
  2. 13q12
  3. 12p13
  4. 12q13

Hint:

B

In agriculture, polyploid crops (like coffee, strawberries, or bananas) tend to produce ________.

  1. more uniformity
  2. more variety
  3. larger yields
  4. smaller yields

Hint:

C

Assume a pericentric inversion occurred in one of two homologs prior to meiosis. The other homolog remains normal. During meiosis, what structure—if any—would these homologs assume in order to pair accurately along their lengths?

  1. V formation
  2. cruciform
  3. loop
  4. pairing would not be possible

Hint:

C

The genotype XXY corresponds to

  1. Klinefelter syndrome
  2. Turner syndrome
  3. Triplo-X
  4. Jacob syndrome

Hint:

A

Abnormalities in the number of X chromosomes tends to have milder phenotypic effects than the same abnormalities in autosomes because of ________.

  1. deletions
  2. nonhomologous recombination
  3. synapsis
  4. X inactivation

Hint:

D

By definition, a pericentric inversion includes the ________.

  1. centromere
  2. chiasma
  3. telomere
  4. synapse

Hint:

A