Review Questions
Which of the following is not true about enzymes:
- They increase ∆G of reactions.
- They are usually made of amino acids.
- They lower the activation energy of chemical reactions.
- Each one is specific to the particular substrate(s) to which it binds.
Hint:
A
An allosteric inhibitor does which of the following?
- Binds to an enzyme away from the active site and changes the conformation of the active site, increasing its affinity for substrate binding.
- Binds to the active site and blocks it from binding substrate.
- Binds to an enzyme away from the active site and changes the conformation of the active site, decreasing its affinity for the substrate.
- Binds directly to the active site and mimics the substrate.
Hint:
C
Which of the following analogies best describes the induced-fit model of enzyme-substrate binding?
- a hug between two people
- a key fitting into a lock
- a square peg fitting through the square hole and a round peg fitting through the round hole of a children’s toy
- the fitting together of two jigsaw puzzle pieces
Hint:
A