Pathogenic Microbiology

Study of the morphology, physiology and immunogenicity of disease-causing bacteria; methods of isolation, identification and control of pathogenic bacteria and diseases.

2 affiliated resources

Search Resources

Selected filters:
Living Dangerously: How the Immune System Maintains Peace with Trillions of Commensal Bacteria while Preventing Pathogenic Invasions
Conditional Remix & Share Permitted

Course Description: In this course, we will examine how the immune system acts to destroy pathogenic invaders while tolerating colonization by necessary commensal bacteria. As a counterpoint, we will also explore sophisticated strategies that help some bacteria evade our immune system. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Material Type:
Unit of Study
Dr Angelina Bilate
Dr Matthias Truttmann
Truttmann Matthias
Date Added:
Microbial Pathogenesis
Unrestricted Use

Learning Objectives in this unit:

Distinguish between signs and symptoms of disease
Explain the difference between a communicable disease and a noncommunicable disease
Compare different types of infectious diseases, including iatrogenic, nosocomial, and zoonotic diseases
Identify and describe the stages of an acute infectious disease in terms of number of pathogens present and severity of signs and symptoms
Summarize Koch’s postulates and molecular Koch’s postulates, respectively, and explain their significance and limitations
Explain the concept of pathogenicity (virulence) in terms of infectious and lethal dose
Distinguish between primary and opportunistic pathogens and identify specific examples of each
Summarize the stages of pathogenesis
Explain the roles of portals of entry and exit in the transmission of disease and identify specific examples of these portals
Explain how virulence factors contribute to signs and symptoms of infectious disease
Differentiate between endotoxins and exotoxins
Describe and differentiate between various types of exotoxins
Describe the mechanisms viruses use for adhesion and antigenic variation
Describe virulence factors unique to fungi and parasites
Compare virulence factors of fungi and bacteria
Explain the difference between protozoan parasites and helminths
Describe how helminths evade the host immune system

Material Type:
Unit of Study
Date Added: