This set of lecture materials, laboratory notes, and activities are ancillary materials created for use with OpenStax Microbiology. The materials were created under a Round Nine Textbook Transformation Grant.

Topics covered include:

The Cell
Prokaryotes
Eukaryotes
Acellular Pathogens
Microbial Metabolism
Microbial Growth
Biochemistry of the Bacterial Genome
Microbial Genetics
Microbial Growth
Antimicrobial Drugs
Pathogenicity
Epidemiology
Immune System

This course focuses on the latest scientific developments and discoveries in the field of nanomechanics, the study of forces and motion on extremely tiny (10-9 m) areas of synthetic and biological materials and structures. At this level, mechanical properties are intimately related to chemistry, physics, and quantum mechanics. Most lectures will consist of a theoretical component that will then be compared to recent experimental data (case studies) in the literature. The course begins with a series of introductory lectures that describes the normal and lateral forces acting at the atomic scale. The following discussions include experimental techniques in high resolution force spectroscopy, atomistic aspects of adhesion, nanoindentation, molecular details of fracture, chemical force microscopy, elasticity of single macromolecular chains, intermolecular interactions in polymers, dynamic force spectroscopy, biomolecular bond strength measurements, and molecular motors.

Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Explores the interaction of radiation with matter at the microscopic level from both the theoretical and experimental viewpoints. Emphasis on radiation effects in biological systems. Topics include energy deposition by various types of radiation, including the creation and behavior of secondary radiations; the effects of radiation on cells and on DNA; and experimental techniques used to measure these radiation effects. Cavity theory, microdosimetry and methods used to simulate radiation track structure are reviewed. Examples of current literature used to relate theory, modeling, and experimental methods. Requires a term paper and presentation. The central theme of this course is the interaction of radiation with biological material. The course is intended to provide a broad understanding of how different types of radiation deposit energy, including the creation and behavior of secondary radiations; of how radiation affects cells and why the different types of radiation have very different biological effects. Topics will include: the effects of radiation on biological systems including DNA damage; in vitro cell survival models; and in vivo mammalian systems. The course covers radiation therapy, radiation syndromes in humans and carcinogenesis. Environmental radiation sources on earth and in space, and aspects of radiation protection are also discussed. Examples from the current literature will be used to supplement lecture material.

Principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Mass transport through membranes: diffusion, osmosis, chemically mediated, and active transport. Electric properties of cells: ion transport; equilibrium, resting, and action potentials. Kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the concepts. For juniors and seniors. Students engage in extensive written and oral communication exercises.

This laboratory manual is intended for use in a biology laboratory course taken by non-science majors, pre-biology, and pre-allied health majors.

Laboratory exercises provide students with experience in basic laboratory skills, gathering and organizing data, measuring and calculating, hypothesis testing, analysis of data, writing, and laboratory safety. The skill sets are designed to promote the development of critical thought and analysis. Students work with living and preserved specimens, and laboratory reagents and equipment.

Delivering a single virus to a cell allows the virus to infect the cell, replicate, and give rise to many progeny viruses. These viruses can then infect many neighboring cells.